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Recently, a new study has shown that NMN, a natural compound, can help improve infertility in diabetic patients. In this article, we will provide information about the effects of diabetes on sperm quality, and methods of using NMN to improve infertility.
Diabetes is a chronic disease that affects the body's ability to produce and use insulin . Diabetes can lead to a range of complications, including nerve damage, kidney disease and even infertility.
In men, diabetes can significantly affect the motility and quality of sperm, as well as the quantity, making it very difficult for couples to conceive, even though they have tried everything to prevent it. cure male infertility. Studies have shown that infertile diabetics often have lower testosterone levels , which reduces sperm count.
Infertility in diabetic patients is a common condition.
Furthermore, diabetes can also damage the blood vessels that supply oxygen and nutrients to the testicles, leading to testicular dysfunction. It will most likely affect the quality and quantity of sperm. High blood glucose levels can also cause oxidative stress or inflammation, both of which can damage sperm and cause infertility in diabetics.
According to the International Diabetes Organization, in 2015, about 10% of the global population had type 2 diabetes. Men with diabetes often have reduced sexual desire and abnormalities. about sperm, or erectile dysfunction, leading to infertility. Although diabetes drugs such as metformin or pioglitazone have shown some promise in helping restore sperm function, more effective drugs are needed and viable adjunctive therapies are needed. Helps restore fertility in men with diabetes.
Studies on rats have shown that treating male diabetic rats with nicotinamide mononucleotide (NMN) increased sperm count, as well as improved testicular structure and function. Furthermore, this group of researchers demonstrated that NMN helps restore the size of the tubules in the testicles, where spermatogenesis takes place, and that enzymes that are important for using glucose for energy increased the number of sperm cells. intake to improve testicular health. These findings have shown that NMN can treat male infertility caused by diabetes.
Research has proven that NMN can cure male infertility caused by diabetes.
The study also treated mice with streptozotocin, a chemotherapy agent that is toxic to pancreatic cells and known to cause type 2 diabetes in mice. In their diabetic mouse model, sperm count was significantly reduced and the rate of abnormal sperm was much higher. NMN treatment reversed reduced sperm count and abnormal sperm count in diabetic rats, and also showed that NMN improved diabetes-induced male infertility.
To test NMN's ability to restore the structure of the testicles in diabetes, the researchers also examined the size of the seminiferous tubules in the testicles that produce cells. precursor of sperm. Type 2 diabetic mice showed a marked reduction in seminiferous tubule area and diameter compared to nondiabetic mice. However, NMN has helped restore these defects. Because structural integrity confers functional capacity, these findings also suggest that NMN may help reverse infertility in diabetic patients.
Because type 2 diabetes is closely linked to impairment of the breakdown of glucose to generate energy for cells in a process called glycolysis, the researchers examined the abundance of these sugar enzymes. stool is very important in the testicles. Although the enzyme's concentration was sharply reduced in the testes of diabetic mice, NMN restored its abundance. These results also showed that NMN improves infertility while helping restore glucose utilization in the testes of diabetic rats, which may help provide the cellular energy needed for the process. sperm production.
Although studies in mice have shown promising results, NMN may be a very effective treatment for infertility in diabetics. However, more research is needed to confirm these findings and determine the optimal dose and duration of NMN supplementation.
Future studies should also look at diabetes drugs such as pioglitazone or metformin as well as NMN to help restore fertility in men with diabetes.
In addition to medications to treat male infertility, men should also eat healthier and exercise every day as a way to combat the side effects of diabetes to reverse infertility. in diabetic patients. In addition, many studies on the effects of age and aging in men have shown that age also affects semen quality and fertility.
Nowadays, in addition to applying measures to help improve diabetes, patients can consider using additional health protection foods containing Nicotinamide Mononucleotide (NMN), which is a precursor enzyme of Coenzyme. NAD. Nicotinamide Mononucleotide is one of the main sources of cellular energy in the body that improves insulin sensitivity, immune function and physical activity levels. Nicotinamide mononucleotide (NMN) can control type II diabetes. The researchers concluded that increasing NAD+ from NMN may be beneficial by improving insulin sensitivity, reducing fat storage, and stabilizing blood sugar levels, thereby helping to effectively treat patients with type II diabetes. than.
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A clinical trial on young and middle-aged runners published widely in the Journal of the International Society of Sports Nutrition showed that Nicotinamide Mononucleotide (NMN) supplementation directly to the process of generating energy through the oxidation of compounds in the body (also known as aerobic capacity).
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